The Drought is the first main area that you will find side quests in Borderlands 3. Finding the side quests are easy, completing them is another thing entirely. Check out this Borderlands 3 The Drought side quest guide to complete them all.
Borderlands 3 The Drought Side Quest Guide
Found the second Good Prospects chest in Vestige but can't reach it? This guide on How To Open The Gate In Sheriffs Building In Borderlands 3 will tell you what must be done in order to gain access to the small room near the jail cells at the back of the Sheriffs building.
The town of Vestige is the new hub in the Bounty Of Blood DLC for Borderlands 3. Check out this Borderlands 3 Bounty Of Blood Vestige Challenge guide to complete them all quickly. Some of these won't be able to be finished until a little later in the DLC.
Vestige, in the Bounty of Blood DLC, has a locked gate behind the vault in the bank. This guide on How To Open Vestige Bank Vault Safe In Borderlands 3 will tell you what you have to do in order to open the gate blocking all of the loot locked away inside.
Bloodsun Canyon is the last new area of the Bounty Of Blood DLC for Borderlands 3. Check out this Borderlands 3 Bounty Of Blood Bloodsun Canyon Challenge guide to complete them all as you go along. There are a couple of tricky ones in this area.